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Betulinic acid

CAS No. 472-15-1

Betulinic acid ( Lupatic acid;Betulic acid )

Catalog No. M14569 CAS No. 472-15-1

A naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Betulinic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    A naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties.
  • Description
    A naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties; shows to be a catalytic inhibitor of Topo II with IC50 values ranging from 0.38 to 58 uM; induces cell death through induction of apoptosis and inhibition of autophagic flux in microglia BV-2 cells.Chemotherapeutic Agents Suspended
  • Synonyms
    Lupatic acid;Betulic acid
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Topoisomerase
  • Recptor
    AminopeptidaseN;EukaryotictopoisomeraseI;HIV-1
  • Research Area
    Cancer
  • Indication
    Chemotherapeutic

Chemical Information

  • CAS Number
    472-15-1
  • Formula Weight
    456.70
  • Molecular Formula
    C30H48O3
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C([C@]1(CC[C@H]2C(C)=C)[C@@]2([H])[C@@]3([H])CC[C@]4([H])[C@@]5(C)CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@]4(C)[C@]3(C)CC1)O
  • Chemical Name
    Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3β)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Potze L, et al. Cell Death Dis. 2014 Apr 10;5:e1169.
2. Seo J, et al. Biomol Ther (Seoul). 2017 Mar 10. doi: 10.4062/biomolther.2016.255.
3. Wada S, et al. Chem Biodivers. 2005 May;2(5):689-94.
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