Cart
sales@molnova.com
Home - Products - Cell Cycle/DNA Damage - Topoisomerase - Betulinic acid

Betulinic acid

CAS No. 472-15-1

Betulinic acid ( Lupatic acid;Betulic acid )

Catalog No. M14569 CAS No. 472-15-1

A naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
50MG 30 Get Quote
100MG 43 Get Quote
500MG 157 Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Betulinic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    A naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties.
  • Description
    A naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties; shows to be a catalytic inhibitor of Topo II with IC50 values ranging from 0.38 to 58 uM; induces cell death through induction of apoptosis and inhibition of autophagic flux in microglia BV-2 cells.Chemotherapeutic Agents Suspended
  • Synonyms
    Lupatic acid;Betulic acid
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Topoisomerase
  • Recptor
    AminopeptidaseN;EukaryotictopoisomeraseI;HIV-1
  • Research Area
    Cancer
  • Indication
    Chemotherapeutic

Chemical Information

  • CAS Number
    472-15-1
  • Formula Weight
    456.70
  • Molecular Formula
    C30H48O3
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C([C@]1(CC[C@H]2C(C)=C)[C@@]2([H])[C@@]3([H])CC[C@]4([H])[C@@]5(C)CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@]4(C)[C@]3(C)CC1)O
  • Chemical Name
    Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3β)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Potze L, et al. Cell Death Dis. 2014 Apr 10;5:e1169.
2. Seo J, et al. Biomol Ther (Seoul). 2017 Mar 10. doi: 10.4062/biomolther.2016.255.
3. Wada S, et al. Chem Biodivers. 2005 May;2(5):689-94.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Zoliflodacin

    Zoliflodacin (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aureus (MIC90: 0.25 μg/mL).

  • Amenamevir

    Amenamevir is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mL).

  • 10-Hydroxycamptothec...

    (S)-10-Hydroxycamptothecin is a clinical therapy agent against hepatoma.

Sign In Join Free